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DNA damage response mechanisms protect mammalian cells from genomic instability and phenotypes such as aging and cancer. In contrast to normal cells, tumors exhibit extreme genomic instability, which can occur at the level of DNA as well as at the chromosomal level. This course reviews the causes and consequences of genomic instability, including manifestations in DNA and chromosomes; the course also provides a thorough review of cellular DNA damage response mechanisms, including detection of damage, checkpoint signaling, and recruitment of repair factors.
RACE Application Status
This module has been submitted and approved for 1.0 hours of continuing education credit in jurisdictions which recognize AAVSB RACE approval.
For additional questions, please contact us at Learning@ACVIM.org.
Dr. Hume received her Doctorate of Veterinary Medicine from Auburn University. She completed a residency in medical oncology at North Carolina State University in 2008 and a research fellowship in the Department of Biomedical Sciences at Cornell University in 2010. She is currently an associate professor in the Department of Clinical Sciences at Cornell University. Her research focuses on understanding how DNA damage response and repair pathways modulate tumor suppression and chemosensitivity, with the ultimate goal of determining how the genetics of a given tumor can be used to best manipulate therapeutic combinations.
ACVIM Diplomates and candidates: $0
ECEIM, ECVIM-CA and ECVN Diplomates and candidates: $30
On demand courses are hosted in ACVIM’s online learning system ACVIM Online, powered by VetBloom.
Individual access has been provided to enrolled participants via email or log in using your ACVIM.org username and password. You will be taken to your Learner Dashboard where any course you are enrolled in will show in the Current Learning section.
All ACVIM Oncology Diplomates and candidates have been automatically enrolled in each Science of Veterinary
The ACVIM has developed nine (9) Science of Veterinary Oncology (SOVO) online courses that are currently available and complimentary for ACVIM members with five (5) more in development and coming soon. These modules offer foundational building blocks of core knowledge areas pertaining to veterinary oncology and were developed based on the Job Task Analysis review performed in 2016. All modules are led by industry experts and each module is RACE-approved.