Principles of Cancer Immunotherapy

On Demand

Course Overview


Immunotherapy is now recognized as the “fourth pillar” of cancer therapy. As immunological approaches are translated into the clinic for human and veterinary cancer patients, it is essential for oncologists and other health care professionals to have a thorough understanding of immunophysiology and immunopathology, as this will allow them to appreciate the balance between the potential benefits and the considerable risks of immunotherapy. This lecture will emphasize general principles of immunotherapy, describe several approaches that have been or are being translated from the laboratory to the clinic, and provide selected examples of how gains in immunotherapy are being translated to companion animals with cancer. The presentation is divided into five sections. The first section will present a brief primer of immunophysiology and immunopathology. The viewer is strongly encouraged to watch the previous lecture in this series entitled, “Building the Immune Environment of Cancer.” The second section will review mechanisms whereby the immunosuppressive barrier can be disrupted and through which the immune system can attack the tumor. The third section will cover a brief history of immunotherapy, illustrating the centuries-old interest in this field. The fourth section will review general approaches to immunotherapy with select examples of their application in companion animals. The fifth and final section will introduce the emerging area of cancer Immunoprophylaxis, which represents the next frontier for cancer immunotherapy.

Learning Objectives:
  • Be able to discuss the mechanisms that initiate, terminate, and suppress immune responses, and their impact on cancer immunotherapy
  • Understand the opportunities and limitations for immunomodulation and immunotherapy across the diversity of cancers
  • Appreciate the myriad approaches that can be used for cancer treatment, and potentially for immunoprevention to reduce cancer risk

RACE Application Status

This module has been submitted and approved for 1.5 hours of continuing education credit in jurisdictions which recognize AAVSB RACE approval.

For additional questions, please contact us at Learning@ACVIM.org.




Jaime Modiano, VMD, PhD

Jaime Modiano, VMD, PhD
Perlman Professor of Oncology and Comparative Medicine Department of Clinical Sciences
University of Minnesota College of Veterinary Medicine


Dr. Jaime Modiano holds the Alvin and June Perlman Endowed Chair of Animal Oncology and is Director of the Animal Cancer Care and Research Program of the College of Veterinary Medicine and the Masonic Cancer Center, University of Minnesota. He completed his training through the Veterinary Medical Scientist Training Program (VMD, PhD) at the University of Pennsylvania, followed by a residency in Clinical Pathology at Colorado State University and a post-doctoral fellowship at the National Jewish Center for Immunology and Respiratory Medicine. Before joining the University of Minnesota, he served on the faculties of Texas A&M University and the University of Colorado Health Sciences Center.


Sponsored by


Course Information

  • Date: Anytime
  • Duration: 75 Minutes
  • Location: Virtual
    • Audience: ACVIM, ECEIM, ECVIM-CA and ECVN Diplomates and candidates
    • Specialty: Oncology
    • Type: On Demand
    • CE Hours: 1.5



ACVIM Diplomates and candidates: $0

ECEIM, ECVIM-CA and ECVN Diplomates and candidates: $30 

Nonmembers: $50



 Already Registered?

On Demand courses are hosted in ACVIM’s online learning system ACVIM Online, powered by VetBloom.


Individual access has been provided to enrolled participants via email or  log in using your ACVIM.org username and password. You will be taken to your Learner Dashboard where any course you are enrolled in will show in the Current Learning section.

All ACVIM Oncology Diplomates and Candidates have been automatically enrolled in each Science of Veterinary

Questions? Check out the ACVIM Online Instructional Guide  or contact  Learning@ACVIM.org


Series Overview

The ACVIM has developed ten (10) Science of Veterinary Oncology (SOVO) online courses that are currently available and complimentary for ACVIM members with four (4) more in development and coming soon. These modules offer foundational building blocks of core knowledge areas pertaining to veterinary oncology and were developed based on the Job Task Analysis review performed in 2016. All modules are led by industry experts and each module is RACE-approved. 




Back To Top