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This session will cover the historical and modern concepts of glucose utilization and energy generation in cancer, how it may affect tumor cell behavior, and strategies for intervention.
This module reviews the biology of CSCs and provides insights into CSC plasticity, interaction with the niche, tumor repopulation and clinical implications of therapeutic response.
The objective of this module is to provide an overview of signal transduction in both normal and neoplastic cells.
This module gives a high-level view of the history of anticancer drugs, a general idea of the current drug discovery process for both small and large molecule drugs.
This module describes the common, currently understood epigenetic mechanisms of mammalian cells that contribute to carcinogenesis.
In this course we discuss the early findings with regard to the kinetics of tumor cell death that lead to current approaches to the treatment of cancer.
This lecture will describe the tumor microenvironment, beginning with the mechanisms that lead to the creation of a tumor niche and continuing through the steps that allow it to evolve to favor tumor growth and dissemination.